Cognitive & Neurological
Dihexa
Angiotensin IV-derived peptide studied for HGF and c-Met activation, synaptogenesis and dendritic spine formation in neuronal models.
Also known asN-hexanoic-Tyr-Ile-(6)-aminohexanoic amide
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 604.8 Da
- Amino acid residues
- 7
- Half-life
- Persistent (weeks in tissue)
- CAS number
- —
Monograph
Specifications
- Research area
- Cognitive & Neurological
- Half-life
- Persistent (weeks in tissue)
- Molecular weight
- 604.8 Da
- Amino acid residues
- 7
- Mechanism of action
- Activates the HGF/c-Met receptor, promoting synaptogenesis and dendritic spine formation. Enhances HGF signalling through a mechanism that does not compete with the ligand.
- Storage and handling
- Store in a cool, dry place; refrigerate if in solution.