Cognitive & Neurological
DSIP
Nonapeptide first isolated from rabbit brain. Studied in slow-wave sleep models and for its effects on opioid receptors and the cortisol rhythm.
Also known asDelta Sleep Inducing Peptide
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 848.9 Da
- Amino acid residues
- 9
- Half-life
- ~30–40 minutes
- CAS number
- —
Monograph
Specifications
- Research area
- Cognitive & Neurological
- Half-life
- ~30–40 minutes
- Molecular weight
- 848.9 Da
- Amino acid residues
- 9
- Mechanism of action
- Modulates the activity of the noradrenergic and serotonergic systems. Activates µ and δ opioid receptors with analgesic effect. Inhibits the release of ACTH and normalizes the circadian rhythm of cortisol.
- Storage and handling
- Refrigerate at 2–8 °C after reconstitution.