Anabolic & Growth Factors
Follistatin 344
Glycoprotein that binds activin and myostatin. Studied as a TGF-β family inhibitor in skeletal muscle and myostatin signalling models.
Also known asFST-344 · Follistatin
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 37800 Da
- Amino acid residues
- 344
- Half-life
- ~30–60 minutes
- CAS number
- —
Monograph
Specifications
- Research area
- Anabolic & Growth Factors
- Half-life
- ~30–60 minutes
- Molecular weight
- 37800 Da
- Amino acid residues
- 344
- Mechanism of action
- Inhibits activin, myostatin, and other proteins of the TGF-β family by directly binding to them and preventing their interaction with receptors. By blocking myostatin, it removes the primary inhibitor of muscle growth.
- Storage and handling
- Refrigerate at 2–8 °C once reconstituted. Highly sensitive to temperature.