Growth Hormone Axis
GHRP-6
Early synthetic GH secretagogue studied at the ghrelin receptor, with neuropeptide Y-mediated orexigenic signalling alongside GH release.
Also known asGrowth Hormone Releasing Peptide-6 · His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 873.0 Da
- Amino acid residues
- 6
- Half-life
- ~15–60 minutes
- CAS number
- —
Monograph
Specifications
- Research area
- Growth Hormone Axis
- Half-life
- ~15–60 minutes
- Molecular weight
- 873.0 Da
- Amino acid residues
- 6
- Mechanism of action
- Ghrelin receptor agonist that activates the GH/IGF-1 axis. It has a strong orexigenic action (appetite stimulant) mediated by neuropeptide Y. It also elevates cortisol and prolactin.
- Storage and handling
- Refrigerate at 2–8 °C after reconstitution. Powder is stable at room temperature for up to 24 months.