Anabolic & Growth Factors
MGF
Locally expressed IGF-1 splice variant studied for satellite cell activation in muscle damage and repair models.
Also known asMechano Growth Factor · IGF-1 Ec
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 2867.2 Da
- Amino acid residues
- 24
- Half-life
- ~30 minutes
- CAS number
- —
Monograph
Specifications
- Research area
- Anabolic & Growth Factors
- Half-life
- ~30 minutes
- Molecular weight
- 2867.2 Da
- Amino acid residues
- 24
- Mechanism of action
- The E peptide of MGF directly activates muscle satellite cells independently of the IGF-1R receptor, stimulating their proliferation and differentiation. It acts as a local signal for muscle damage and repair.
- Storage and handling
- Refrigerate at 2–8 °C after reconstitution. Highly sensitive to degradation.