Semaglutide

Also known as: Ozempic · Wegovy · Rybelsus

Mechanism of action

GLP-1 receptor agonist that stimulates glucose-dependent insulin secretion, inhibits glucagon, delays gastric emptying, and acts on the hypothalamus to reduce appetite and caloric intake.

Reported research ranges

0.25 mg subcutaneously per week (initial), escalating to 2.4 mg/week based on tolerance.

Reported adverse effects

Nausea, vomiting, diarrhea (especially at the onset), constipation, pancreatitis (rare), diabetic retinopathy.

Storage and handling

Refrigerate at 2–8 °C. Do not freeze. Once in use, it can be stored at room temperature for up to 56 days.

This material is published for scientific and educational reference. It is not medical advice, not a treatment recommendation, and not an offer to sell. Compounds discussed are for research and laboratory use only.