Metabolic & Body Composition
Semaglutide
Long-acting GLP-1 analogue studied at GLP-1R for glucose-dependent insulin secretion, gastric emptying and hypothalamic appetite signalling.
Also known asOzempic · Wegovy · Rybelsus
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 4113.6 Da
- Amino acid residues
- 31
- Half-life
- ~7 days
- CAS number
- —
Monograph
Specifications
- Research area
- Metabolic & Body Composition
- Half-life
- ~7 days
- Molecular weight
- 4113.6 Da
- Amino acid residues
- 31
- Mechanism of action
- GLP-1 receptor agonist that stimulates glucose-dependent insulin secretion, inhibits glucagon, delays gastric emptying, and acts on the hypothalamus to reduce appetite and caloric intake.
- Storage and handling
- Refrigerate at 2–8 °C. Do not freeze. Once in use, it can be stored at room temperature for up to 56 days.