Cognitive & Neurological
Semax
ACTH(4-10) analogue studied for BDNF and NGF expression and for dopaminergic and serotonergic modulation in neuroplasticity models.
Also known asMet-Glu-His-Phe-Pro-Gly-Pro
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 813.9 Da
- Amino acid residues
- 7
- Half-life
- ~7 minutes (plasma); effects lasting 12 hours.
- CAS number
- —
Monograph
Specifications
- Research area
- Cognitive & Neurological
- Half-life
- ~7 minutes (plasma); effects lasting 12 hours.
- Molecular weight
- 813.9 Da
- Amino acid residues
- 7
- Mechanism of action
- Increases levels of BDNF and NGF in the hippocampus and cortex. Modulates the dopaminergic and serotonergic systems, enhances neurotransmission, and promotes neuroplasticity. Exhibits anti-inflammatory properties in the CNS.
- Storage and handling
- Refrigerate at 2–8 °C. Sensitive to temperature and light.