Longevity & Cellular Health
SS-31
Cardiolipin-binding tetrapeptide studied for respiratory chain stability, reactive oxygen species and ATP synthesis in mitochondria.
Also known asElamipretide · MTP-131 · Bendavia
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 639.8 Da
- Amino acid residues
- 4
- Half-life
- ~2 hours
- CAS number
- —
Monograph
Specifications
- Research area
- Longevity & Cellular Health
- Half-life
- ~2 hours
- Molecular weight
- 639.8 Da
- Amino acid residues
- 4
- Mechanism of action
- It accumulates in the inner mitochondrial membrane and binds to cardiolipin, stabilizing the respiratory chain complexes (I, III, IV, V). It reduces the production of reactive oxygen species (ROS) and optimizes ATP synthesis.
- Storage and handling
- Refrigerate at 2–8 °C after reconstitution.