Immune & Anti-inflammatory
Thymosin Alpha-1
Thymic 28-residue peptide studied for TLR2 and TLR4 signalling, T cell maturation and interferon and IL-2 production.
Also known asTα1 · Thymalfasin · Zadaxin
Identity
Residue chain
One bead per amino acid residue, N-terminus to C-terminus. Long chains are shown truncated.
- Molecular weight
- 3108.4 Da
- Amino acid residues
- 28
- Half-life
- ~2 hours
- CAS number
- —
Monograph
Specifications
- Research area
- Immune & Anti-inflammatory
- Half-life
- ~2 hours
- Molecular weight
- 3108.4 Da
- Amino acid residues
- 28
- Mechanism of action
- Activates the maturation and differentiation of T cells in the thymus via TLR2/TLR4. Increases the production of IL-2, type I and II interferons, and NK cells. Reduces tumor-induced immunosuppression and enhances immune surveillance.
- Storage and handling
- Refrigerate at 2–8 °C after reconstitution. Powder is stable at room temperature.