Synedica Laboratories

Health & Peptide Science

Learning paths

Each path collects existing articles into a reading order, starting from fundamentals and building toward applied research topics.
Learning paths
4
modules
17
articles
39
  1. 01Introductory4 modules · 10 articles

    Introduction to peptide research

    A starting path through peptide research: what the compounds are, how purity and identity are established, what the regulatory framework covers, and how to judge a published claim.

    • Understand what peptides are and how they differ from proteins and free amino acids.
    • Read the analytical data that establishes identity and purity for a research lot.
    • Follow how purity is measured by HPLC-UV and confirmed by mass spectrometry.
    • Understand what the research-use classification covers and what it excludes.
    Start path
    1. 01Research fundamentals2
    2. 02Production and purity2
    3. 03Regulation and research use3
    4. 04Evidence and public claims3
  2. 02Intermediate3 modules · 4 articles

    GH secretagogues and the IGF-1 axis

    An intermediate path through growth hormone secretagogue research: ipamorelin, CJC-1295, sermorelin and tesamorelin, how each engages the GH axis, and what the preclinical readouts measure.

    • Understand the mechanisms of action of GH secretagogues.
    • Compare secretagogues by receptor target and pharmacokinetics.
    • Follow the GHRH and somatostatin balance that sets endogenous GH release.
    • Trace hepatic IGF-1 synthesis downstream of a GH pulse.
    Start path
    1. 01Introduction to GH secretagogues1
    2. 02Comparisons and combinations2
    3. 03IGF-1 axis readouts1
  3. 03Intermediate3 modules · 8 articles

    Metabolic peptides and adipose tissue research

    An intermediate path through metabolic peptide research: retatrutide, AOD-9604 and SLU-PP-332, the lipolytic cascade in adipocytes, and the appetite circuits these compounds act on.

    • Follow the HSL and ATGL cascade that releases fatty acids from adipocytes.
    • Compare retatrutide, AOD-9604 and SLU-PP-332 by receptor target.
    • Read depot differences between visceral and subcutaneous adipose tissue.
    • Locate GLP-1R, MC4R and GHS-R1a in the hypothalamic appetite circuits.
    Start path
    1. 01Mechanisms and comparisons2
    2. 02Peptides in metabolic research4
    3. 03Incretin receptor agonism2
  4. 04Introductory7 modules · 17 articles

    Peptides in ageing and longevity research

    An introductory path through the compounds that recur in ageing research: NAD+, GHK-Cu, Selank and the melanocortin peptides, with the pathways and readouts each one is studied through.

    • Review which peptides recur in ageing research and why.
    • Read what GHK-Cu research reports in skin and hair follicle models.
    • Follow NAD+ availability through sirtuin activity and DNA repair.
    • Review Selank work on GABA-A modulation and BDNF expression.
    Start path
    1. 01Starting points2
    2. 02GHK-Cu in skin and hair models2
    3. 03NAD+ and cellular ageing3
    4. 04Selank, Semax and cognition3
    5. 05Melanocortin signalling3
    6. 06Collagen and cosmetic peptides2
    7. 07Neuropeptides and telomeres2