Synedica Laboratories

Introductory

Peptides in ageing and longevity research

An introductory path through the compounds that recur in ageing research: NAD+, GHK-Cu, Selank and the melanocortin peptides, with the pathways and readouts each one is studied through.
modules
7
articles
17
Reading time
41 min read

Path overview

  1. 01Starting points2
  2. 02GHK-Cu in skin and hair models2
  3. 03NAD+ and cellular ageing3
  4. 04Selank, Semax and cognition3
  5. 05Melanocortin signalling3
  6. 06Collagen and cosmetic peptides2
  7. 07Neuropeptides and telomeres2

What this path covers

  • Review which peptides recur in ageing research and why.
  • Read what GHK-Cu research reports in skin and hair follicle models.
  • Follow NAD+ availability through sirtuin activity and DNA repair.
  • Review Selank work on GABA-A modulation and BDNF expression.
  • Compare melanocortin receptor targets across PT-141 and Melanotan II.
  1. 01

    Module 01

    Starting points

    1. 01NAD+ biosynthesis and the sirtuins4 min read
    2. 02Selank, a tuftsin-derived heptapeptide3 min read
  2. 02

    Module 02

    GHK-Cu in skin and hair models

    1. 01GHK-Cu and hair follicle research1 min read
    2. 02GHK-Cu and collagen in skin research1 min read
  3. 03

    Module 03

    NAD+ and cellular ageing

    1. 01NAD+ decline and cellular senescence3 min read
    2. 02Mitochondrial NAD+ pools and complex I3 min read
    3. 03Peptides studied in ageing research in 20263 min read
  4. 04

    Module 04

    Selank, Semax and cognition

    1. 01Selank and Semax compared2 min read
    2. 02BDNF and TrkB signalling in peptide research3 min read
    3. 03Neuropeptides in preclinical anxiety models2 min read
  5. 05

    Module 05

    Melanocortin signalling

    1. 01Bremelanotide at the melanocortin receptors3 min read
    2. 02MC3R and MC4R distribution in the brain3 min read
    3. 03Melanotan II and the melanocortin receptors2 min read
  6. 06

    Module 06

    Collagen and cosmetic peptides

    1. 01Hydrolysed collagen and bioactive peptides1 min read
    2. 02Cosmetic peptides and research peptides1 min read
  7. 07

    Module 07

    Neuropeptides and telomeres

    1. 01How neuropeptides differ from transmitters3 min read
    2. 02Telomeres, Epitalon and TERT activation3 min read
All learning paths